Kirkwood F. Adams Jr., M.D., is Associate Professor of Medicine and Radiology in the Division of Cardiology, University of North Carolina at Chapel Hill, where he founded and for many years directed the UNC Heart Failure Program and served as the first transplant cardiologist for two decades. Dr. Adams has been involved in more than 130 completed grant- and industry-funded research projects, and he is currently leading or participating in multiple drug development trials, several registry and database studies, and NIH/NHLBI-funded trials. Dr. Adams is the principal investigator for the national multicenter database group, UNITE-HF, which focuses on registries of patients with heart failure. In addition to drug development for acute and chronic heart failure, his current research interests are heavily focused on personalized medicine with ongoing projects related to novel biomarkers for heart failure, pharmacogenomics of heart failure therapeutics, and biomarker guided therapy for improving outcomes in CHF. He is very actively involved on the Executive Committee for the NHLBI sponsored trial of NT- proBNP guided therapy known as the GUIDE-IT Trial.